Antimicrobial Activity of Chemoconstituents of Roots of Salacia Macrosperma
نویسندگان
چکیده
The ethanolic extract of roots of Salacia macrosperma (Hippocrataceae) exhibited significant in vitro antimicrobial activity. The ethanolic extract was fractionated with different solvents and all the fractions were screened for their antimicrobial spectrum against eight gram-positive, five gram-negative and ten fungal strains. Chloroform fraction followed by benzene fraction of enthanolic extract showed significant antimicrobial effect against all the microorganisms tested. The dose-dependent activity of fractions was evaluated against selected microbial strains and compared with appropriate standards.
منابع مشابه
Salacia as an ayurvedic medicine with multiple targets in diabetes and obesity
The genus, Salacia belongs to the family, Celastraceae and is distributed across the world. Roots and stems of Salacia are used mainly as antidiabetic agents in traditional system of medicine such as Ayurveda and Unani. The roots are either chewed directly or taken in dried powdered form or as decoction. Apart from antidiabetic activity, several species of the genus Salacia are known to possess...
متن کاملPharmaceutical Investigations on Salacia Macrosperma-1
The chloroform, ethanol (95%) and aqueous extracts of roots of Salacia macrosperma (Hippocrataceae) were prepared by double maceration followed by vacuum evaporation. All the extracts were subjects to qualitative chemical tests to find out phytoconstituents present in them. The ethanolic extract showed significant hypoglycemic activity in fasted rabbits. The activity of ethanolic extract was al...
متن کاملEvaluation of Antioxidant Properties of Salacia Macrosperma Leaf Extracts
In the present study experiments were carried out to determine the total phenolic content and their comparative antioxidant activities in relation to phenol content employing Folin-ciocalteu, DPPH, and ABTS assays of the different solvent extracts of the plant S. macrosperma. It was found that on an average, the plant extract with higher levels of phenol content had higher antioxidant activity....
متن کاملAntimicrobial Activity of Root Bark of Salacia reticulata
Antimicrobial activity of chloroform and methanolic extracts of Salacia reticulata were tested against gram positive, gram negative and fungus strains using zone of inhibition and minimum inhibitory concentrations. It was observed that both extracts have inhibitory effect towards all microorganisms used in the test. Chloroform extract was more effective than methanolic extract.
متن کاملAntimicrobial Properties of Eranthemum roseum (Vahl) R.Br.
Antimicrobial activity of the roots of Eranthemum roseum (Vahl) R.Br. (Dasmuli), were tested against different bacteria (including Escherichia coli, Staphylococcus aureus, Bacillus subtilis, Shigella sonnei, Klebsiella pneumoniae, Salmonella typhi, Proteus vulgaris, Pseudomonas aeruginosa) and fungi (such as Candida albicans and Aspergillus niger) by cup plate diffusion method. Minimal Inhibito...
متن کامل